Artificial gametes: new paths to parenthood?

Artificial gametes: new paths to parenthood?

A number of recent papers have described the successful derivation of egg and sperm precursor cells from mouse embryonic stem cells—so-called ‘‘artificial’’ gametes. Although many scientific questions remain, this research suggests numerous new possibilities for stem cell research and assisted reproductive technology, if a similar breakthrough is achieved with human embryonic stem cells. The no...

Artificial gametes from stem cells

The generation of artificial gametes is a real challenge for the scientific community today. In vitro development of human eggs and sperm will pave the way for the understanding of the complex process of human gametogenesis and will provide with human gametes for the study of infertility and the onset of some inherited disorders. However, the great promise of artificial gametes resides in their...

Philosophy and Theology: Artificial Gametes

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Parenthood, genes, and gametes: the family law and trusts and estates perspectives.

Stem cell-derived gametes, iterated in vitro reproduction, and genetic parenthood.

This special issue of the Journal incorporates a series of articles on ethical questions raised by stem cell-derived gametes (SCDGs), understood here as gametes or gamete-like cells created in the laboratory from human pluripotent stem cells. The series includes five original research papers covering a wide range of ethical questions: Robert Sparrow’s feature article sets out to stimulate debat...